SAB5700817

Anti-p53 antibody produced in rabbit

• Sinônimo(s): BCC7, LFS1, P53, TP53, TRP53, Tp53, Trp53, bbl, bfy, bhy, p44, p53
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 43
• reatividade de espécies: human, rat, mouse
• concentração: 1.14 mg/ml
• técnica(s): ChIP: 1:20-1:50; immunohistochemistry: 1:50-1:200; immunoprecipitation (IP): 1:20-1:50; western blot: 1:3000-1:6000
• nº de adesão UniProt: P02340
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... TP53(7157) ; mouse ... Trp53(22059)

Descrição

Descrição geral

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

Imunogênio

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p53 (NP_000537.3).

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20℃. Avoid freeze / thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable