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SAB5500022

Sigma-Aldrich

Anti-E-Cadherin antibody, Rabbit monoclonal

clone SP64, recombinant, expressed in proprietary host, affinity isolated antibody

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100 μL
R$ 1.431,00

R$ 1.431,00


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100 μL
R$ 1.431,00

About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

R$ 1.431,00


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fonte biológica

rabbit

Nível de qualidade

recombinante

expressed in proprietary host

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

SP64, monoclonal

reatividade de espécies

human (tested)

técnica(s)

immunoblotting: 1:25
immunohistochemistry: 1:100

Isotipo

IgG

nº de adesão UniProt

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... CDH1(999)

Descrição geral

E-cadherin (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

Imunogênio

Recombinant protein encoding aa 600-707 of human cadherin-E.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Oncology letters, 13(4), 2059-2070 (2017-04-30)
Human bone marrow stromal cells (hBMSCs) may contribute to the growth of tyrosine kinase inhibitor (TKI)-resistant chronic myelogenous leukemia (CML). However, there are certain differences in biology between CML and Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Little is known about
Luis G V Fernandes et al.
Frontiers in microbiology, 14, 1199660-1199660 (2023-07-10)
Leptospirosis is a worldwide zoonosis caused by pathogenic and virulent species of the genus Leptospira, whose pathophysiology and virulence factors remain widely unexplored. Recently, the application of CRISPR interference (CRISPRi) has allowed the specific and rapid gene silencing of major
Juan Zhou et al.
Oncology reports, 39(4), 1783-1792 (2018-02-03)
Chemotherapy is one of the methods to treat patients with non-small cell lung cancer (NSCLC) developing resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), such as gefitinib. Previous studies revealed that the sensitivity to chemotherapy may depend

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