SAB4702104

Monoclonal Anti-CD271, purified produced in mouse

• Sinônimo(s): NGFR, TNFRSF16, p75NGFR, p75NTR
• Código UNSPSC: 12352203

Propriedades

• conjugado: unconjugated
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: NGFR5, monoclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: human, ( Non-human primates), ( Rabbit), ( Cat)
• concentração: 1 mg/ml
• técnica(s): flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Isotipo: IgG1
• nº de adesão UniProt: P08138
• temperatura de armazenamento: 2-8°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... NGFR(4804)

Descrição

Descrição geral

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Especificidade

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

Imunogênio

Purified CD271 protein isolated from human melanoma cell line A875

forma física

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota de preparo

Purified by protein-A affinity chromatography.

Armazenamento e estabilidade

Store at 2-8°C. Do not freeze.

Outras notas

The antibody solution should be gently mixed before use.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable