SAB4702004

Monoclonal Anti-NG2 PE produced in mouse

• Sinônimo(s): CSPG4, Chondroitin sulfate proteoglycan 4, MCSP, MSK16
• Código UNSPSC: 12352203

Propriedades

• conjugado: phycoerythrin (R-PE) conjugate
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: 7.1, monoclonal
• forma: buffered aqueous solution
• reatividade de espécies: human
• técnica(s): flow cytometry: suitable
• Isotipo: IgG1
• nº de adesão UniProt: Q6UVK1
• temperatura de armazenamento: 2-8°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CSPG4(1464)

Descrição

Descrição geral

NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.

Especificidade

The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.

Imunogênio

Human bone marrow stromal cells infected with SV-40

forma física

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota de preparo

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Armazenamento e estabilidade

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Outras notas

The antibody solution should be gently mixed before use.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable