SAB4503974

Anti-phospho-PLK1 (pThr²¹⁰) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.43

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 68 kDa
• reatividade de espécies: human, mouse, rat
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100
• nº de adesão NCBI: P53350
• nº de adesão UniProt: P53350
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pThr210)
• Informações sobre genes: human ... PLK1(5347)

Descrição

Descrição geral

Human polo-like kinase 1 (PLK1) is a serine/threonine kinase, that is located on human chromosome 16p12.

Imunogênio

The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Thr210.

Immunogen Range: 176-225

Ações bioquímicas/fisiológicas

Polo-like kinase 1 (PLK1) plays an important role in the functional maturation of mitotic centrosomes. It actively participates in the development of the cell cycle. This gene is considered as an important therapeutic target as it is overexpressed in several cancer types.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable