SAB4503968

Anti-phospho-PECAM-1 (pTyr⁷¹³) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 82 kDa
• reatividade de espécies: rat, human, mouse
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• nº de adesão NCBI: P16284
• nº de adesão UniProt: P16284
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr713)
• Informações sobre genes: human ... PECAM1(5175)

Descrição

Descrição geral

The platelet and endothelial cell adhesion molecule 1 (PECAM1) is also termed as cluster of differentiation 31 (CD31). It belongs to the immunoglobulin (Ig) superfamily. This gene codes for a 130kDa protein and is located on human chromosome 17. PECAM1 is expressed on the surface of circulating platelets, monocytes, neutrophils and selected T-cell subsets.

Imunogênio

The antiserum was produced against synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyr713.

Immunogen Range: 686-735

Ações bioquímicas/fisiológicas

The platelet and endothelial cell adhesion molecule 1 (PECAM1) participates in leukocyte-endothelial interaction.This protein has a major role in the adhesion cascade leading to leukocyte extravasation during the inflammatory process. PECAM1 also plays a role during the development of T cell.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable