SAB4503839

Anti-phospho-SYK (pTyr⁵²⁵) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 72 kDa
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P43405
• nº de adesão UniProt: P43405
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr525)
• Informações sobre genes: human ... SYK(6850)

Descrição

Descrição geral

Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells. SYK is mapped to human chromosome 9q22.

Imunogênio

The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr525.

Immunogen Range: 491-540

Aplicação

Anti-phospho-SYK (pTyr525) antibody has been used in immunohistochemistry.

Ações bioquímicas/fisiológicas

Spleen tyrosine kinase (SYK), as a tumor suppressor gene helps to prevent the development and metastasis of breast cancer cells. It participates in B-cell receptor signaling. This protein helps to phosphorylate the α-tubulin subunits of microtubules.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable