SAB4502966

Anti-Tyrosine Hydroxylase Antibody

rabbit polyclonal

• Sinônimo(s): TH isoform 3, TH isoform a, TH-4, TY3H, TYH
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• Nome do produto: Anti-Tyrosine Hydroxylase, N-Terminal antibody produced in rabbit, affinity isolated antibody
• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 58 kDa
• reatividade de espécies: rat, mouse, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P07101
• nº de adesão UniProt: P07101
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... TH(7054)

Descrição

Descrição geral

Anti-Tyrosine Hydroxylase Antibody detects endogenous levels of total Tyrosine Hydroxylase protein.

The TH (tyrosine Hydroxylase) gene codes for a homotetramer that contains catalytic, regulatory, and tetramerization domains in each of its subunit.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase.

Immunogen Range: 41-90

Aplicação

Anti-Tyrosine Hydroxylase, N-Terminal antibody produced in rabbit has ben used in immunohistochemistry.

Ações bioquímicas/fisiológicas

The conversion of l-tyrosine into l-DOPA (L-3,4-dihydroxyphenylalanine) is catalyzed by tyrosine hydroxylase (TH), which is the rate-limiting step in the in the synthesis of catecholamines such as dopamine and also other necessary hormones and neuromodulators. The TH enzyme deficiency results in low levels of dopamine, which is characterised in Parkinson′s disease.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable