SAB4501435

Anti-APBB2 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Amyloid β A4 precursor protein-binding family B member 2, Fe65-like protein
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 83 kDa
• reatividade de espécies: human, mouse
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: Q92870
• nº de adesão UniProt: Q92870
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... APBB2(323)

Descrição

Descrição geral

The gene APBB2 (amyloid β precursor protein binding family B member 2) is mapped to human chromosome 4p13.

Imunogênio

The antiserum was produced against synthesized peptide derived from human APBB2.

Immunogen Range: 471-520

Ações bioquímicas/fisiológicas

The gene APBB2 (amyloid β precursor protein binding family B member 2), also referred to as FE65-like 1, encodes an adaptor protein that binds to the cytoplasmic domain of β-amyloid precursor protein (βAPP) and processes it to form β-amyloid (Aβ). Over-expression of APBB2 leads to an accumulation of Aβ in senile plaques seen in patients with Alzheimer′s disease (AD). Mutations in this gene have been associated with AD.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable