SAB4300425

Anti-GRIN2B (Ab-1474) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-MGC142178 antibody produced in rabbit, Anti-MGC142180 antibody produced in rabbit, Anti-NMDAR2B antibody produced in rabbit, Anti-NR2B antibody produced in rabbit, Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody produced in rabbit
• Número MDL: MFCD00243314
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: ~190 kDa
• reatividade de espécies: human, rat, mouse
• concentração: 1 mg/mL
• técnica(s): indirect immunofluorescence: 1:100-1:200
• Isotipo: IgG
• sequência de imunogênio: (H-V-Y-E-K)
• nº de adesão NCBI: NP_000825.2
• nº de adesão UniProt: Q13224
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... GRIN2B(2904)

Descrição

Descrição geral

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes for N-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to the N-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1.

Imunogênio

Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B.

Ações bioquímicas/fisiológicas

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson′s disease and bipolar disorder.

Características e benefícios

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Descrição-alvo

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable