SAB4200270

Anti-PSMB9 antibody, Mouse monoclonal

clone LMP2-37, purified from hybridoma cell culture

• Sinônimo(s): Monoclonal Anti-LMP2, Monoclonal Anti-PSMB6i, Monoclonal Anti-RING12, Monoclonal Anti-beta1i, Monoclonal Anti-proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
• Código UNSPSC: 12352203

Propriedades

• fonte biológica: mouse
• conjugado: unconjugated
• forma do anticorpo: purified from hybridoma cell culture
• tipo de produto de anticorpo: primary antibodies
• clone: LMP2-37, monoclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 17 kDa
• reatividade de espécies: human, mouse, rat
• concentração: ~1.0 mg/mL
• técnica(s): immunocytochemistry: suitable; indirect ELISA: suitable; western blot: 1.0-2.0 μg/mL using extracts of rat spleen
• Isotipo: IgG2a
• nº de adesão UniProt: P28065
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... PSMB9(5698)

Descrição

Descrição geral

Monoclonal Anti-PSMB9 (mouse IgG2a isotype) is derived from the hybridoma LMP2-37 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human PSMB9 recombinant protein. Proteasome 20S subunit beta 9 (PSMB9) is present in the major histocompatibility complex (MHC) class II region. γ-interferon triggers the synthesis of three proteasomal subunits-PSMB9 (β1i), PSMB10 (β2i) and PSMB8 (β5i), which is a part of immunoproteasome.

Imunogênio

human PSMB9, recombinant protein.

Aplicação

Monoclonal Anti-PSMB9 antibody produced in mouse has been used in:

• flow cytometry
• enzyme linked immunosorbent assay (ELISA)
• immunoblotting
• immunocytochemistry

Ações bioquímicas/fisiológicas

Proteasome 20S subunit beta 9 (PSMB9) is used during antigen presentation. Aberrant levels of PSMB9 is involved in autoimmune disorders such as primary Sjogren′s syndrome and uterine leiomyosarcomas. The proteasome is a multicatalytic proteinase complex, which is involved in the regulation of essential cellular processes such as transcription, cell cycle progression, differentiation, apoptosis and in the control of stress and immune responses.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable