SAB3501242

Anti-SCARB1 antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41
• conjugado: unconjugated
• application: IF; IHC; WB
• clone: polyclonal
• reatividade de espécies: rat, human, mouse
• técnica(s): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: liquid
• reatividade de espécies: rat, human, mouse
• concentração: 1 mg/mL
• técnica(s): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG
• nº de adesão UniProt: Q8WTV0
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SCARB1(949)

Descrição

Descrição geral

SCARB1 Antibody: Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus.

Imunogênio

SCARB1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SCARB1.The immunogen is located within amino acids 70 - 120 of SCARB1.

Aplicação

SCARB1 antibody can be used for detection of SCARB1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

forma física

Supplied in PBS containing 0.02% sodium azide.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable