SAB3500124

Monoclonal Anti-CD4L antibody produced in mouse

clone 9H5A8, purified immunoglobulin, buffered aqueous solution

• Sinônimo(s): Anti-CD4 antigen, Anti-CD4 receptor
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 9H5A8, monoclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: mouse, human, rat
• técnica(s): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• nº de adesão UniProt: P01730
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CD4(920)

Descrição

Descrição geral

Cluster of differentiation (CD4) encodes a T-cell surface glycoprotein CD4. In human chromosome, the gene CD4 is localized on 12p13.31.

Imunogênio

raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.

Ações bioquímicas/fisiológicas

Cluster of differentiation (CD4) mutation in single nucleotide causes OKT4 (Leu-3 T4) epitope deficiency. CD4 plays a major role in collateral artery formation by recruiting macrophages at the active site and through triggering the synthesis of arteriogenic cytokines.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descrição-alvo

CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.

forma física

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable