SAB1409054

Monoclonal Anti-FTL antibody produced in mouse

clone X1, purified immunoglobulin, buffered aqueous solution

• Sinônimo(s): MGC71996
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: X1, monoclonal
• forma: buffered aqueous solution
• peso molecular: antigen 44.99 kDa
• reatividade de espécies: human
• técnica(s): immunoprecipitation (IP): suitable; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1-5 μg/mL
• Isotipo: IgG1κ
• nº de adesão NCBI: BC004245
• nº de adesão UniProt: P02792
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... FTL(2512)

Descrição

Descrição geral

Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. This gene encodes the light subunit of the ferritin protein. It is composed of 24 subunits of the heavy and light ferritin chains.(provided by RefSeq). In humans, the heavy H and the light L chains are made up of 183 and 175 amino acids, respectively. FTL (ferritin) is a heteropolymer, located on human chromosome 19q13. Ferritins centralize iron in their inner compartment as a bioavailable iron oxide biomineral.

Imunogênio

FTL (AAH04245, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD

Ações bioquímicas/fisiológicas

Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
L-Ferritin subunits deliver the scaffold for a trinuclear peroxo-bridged cluster.

forma física

Solution in phosphate buffered saline, pH 7.4

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable