SAB1407182

Anti-EPB41L3 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

• Sinônimo(s): 4.1B, DAL-1, DAL1, FLJ37633, KIAA0987
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen ~96.5 kDa
• reatividade de espécies: human
• técnica(s): western blot: 1 μg/mL
• nº de adesão NCBI: BC006141.1
• nº de adesão UniProt: Q9Y2J2
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... EPB41L3(23136)

Descrição

Descrição geral

Erythrocyte membrane protein band 4.1-like 3 (EPB41L3)/protein 4.1B is expressed at high levels in the brain and neurons. Adipose tissue, kidney, testis, adrenal gland, and placenta also show high expression of EPB41L3. It is moderately expressed in the lungs and intestines. EPB41L3 gene is located on human chromosome 18p11.31. Protein 4.1B belongs to the protein 4.1 superfamily of proteins. It has an N-terminal 4.1/ezrin/radixin/moesin (FERM) domain.

Imunogênio

EPB41L3 (AAH06141.1, 1 a.a. ~ 865 a.a) full-length human protein.

Sequence
MTTESGSDSESKPDQEAEPQEAAGAQGRAGAPVPEPPKEEQQQALEQFAAAAAHSTPVRREVTDKEQEFAARAAKQLEYQQLEDDKLSQKSSSSKLSRSPLKIVKKPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPKKFLTLGSKFRYSGRTQAQTRRASALIDRPAPYFERSSSKRYTMSRSLDGASVNENHEIYMKDSMSAAEVGTGQYATTKGISQTNLITTVTPEKKAEEERDEEEDKRRKGEEVTPISAIRHEGKTDSERTDTAADGETTATEELEKTQDDLMKHQTNISELKRTFLETSTDTAVTNEWEKRLSTSPVRLAARQEDAPMIEPLVPEEKMETKTESSGIETEPTVHHLPLSTEKVVQETVLVEERRVVHASGDASYSAGDSGDAAAQPAFTGIKGKEGSALTEGAKEEGGEEVAKAVLEQEETAAASRERQEEQSAAIHISETLEQKPHFESSTVKTETISFGSVSPGGVKLEISTKEVPVVHTETKTITYESSQVDPGTDLEPGVLMSAQTITSETTSTTTTTHITKTVKGGISETRIEKRIVITGDADIDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEITPEDGED

Ações bioquímicas/fisiológicas

Erythrocyte membrane protein band 4.1-like 3 (EPB41L3)/protein 4.1B helps in linking cellular receptors with the cytoskeleton. It possesses tumor-suppressive action. In human, overexpression of EPB41L3 gene can stimulate apoptosis in breast cancer, non-small cell lung cancer, and meningioma cells.

forma física

Solution in phosphate buffered saline, pH 7.4

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable