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SAB1303013

Sigma-Aldrich

ANTI-IL17RB (CENTER) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Sinônimo(s):

Cytokine receptor CRL4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, IL-17Rh1, IL17BR, IL17RB, IL17Rh1, Interleukin-17 receptor B, Interleukin-17B receptor, UNQ2501/PRO19612

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400 μL
R$ 3.457,00

R$ 3.457,00

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.43

R$ 3.457,00

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fonte biológica

rabbit

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

IgG fraction of antiserum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

peso molecular

55885 Da

reatividade de espécies

human

técnica(s)

flow cytometry: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:250-1:500

nº de adesão UniProt

Q9NRM6

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... IL17RB(55540)

Categorias relacionadas

Descrição geral

Interleukin 17 receptor B (IL-17RB) belongs to the IL-17 receptor family. IL17RB, the receptor for interleukin 17 B (IL17B) is expressed at a high level in the liver, kidney, and other peripheral organs. It is also expressed in memory and effector T lymphocytes. IL17RB gene is located on human chromosome 3p21.1.

Aplicação

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Ações bioquímicas/fisiológicas

Interleukin 17 receptor B (IL-17RB) might be considered in thyroid cancer therapy as a potential therapeutic target. IL17RB exhibits much efficient binding avidity to interleukin 17 E (IL17E). IL-17RB is overexpressed in pancreatic, gastric, and prostate cancers.

forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
SA100916BC
SH090918AN

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Alfonso Lavorgna et al.
PLoS pathogens, 10(10), e1004418-e1004418 (2014-10-24)
Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult T-cell leukemia (ATL) and the neuroinflammatory disease HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 Tax protein functions as a potent viral oncogene that constitutively
Qingli Bie et al.
Scientific reports, 6, 25447-25447 (2016-05-06)
Inflammation is a critical component involved in tumor progression. Interleukin-17 (IL-17) belongs to a relatively new family of cytokines that has been associated with the progression of cancers. However, the role of IL-17B/IL-17RB (IL-17 receptor B) signaling to stemness of
Lei Ren et al.
Molecular immunology, 90, 126-135 (2017-07-18)
IL-17RB, a member of the IL-17 receptor family that can be activated by IL-17B, has been proved to be involved in inflammatory diseases and cancers. However, the function of IL-17RB in thyroid cancer is still unknown. In this study, IL-17RB
Gary M Hunninghake et al.
BMC pulmonary medicine, 11, 17-17 (2011-04-09)
The relationships between total serum IgE levels and gene expression patterns in peripheral blood CD4+ T cells (in all subjects and within each sex specifically) are not known. Peripheral blood CD4+ T cells from 223 participants from the Childhood Asthma

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