GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
Imunogênio
GDF9 (NP_005251, 35-69) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF9.
forma física
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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