R9404

Anti-RhoA antibody produced in rabbit

~2 mg/mL, affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-p21 Rho
• Número MDL: MFCD09265373
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: antigen ~21 kDa
• reatividade de espécies: monkey, mouse, human
• concentração: ~2 mg/mL
• técnica(s): western blot: 1-2 μg/mL using HEK293 cells expressing human RhoA/ Hela cell extract
• nº de adesão UniProt: P61586
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... RHOA(387)

Descrição

Descrição geral

RhoA (ras homolog family member A) belongs to the Rho GTPase family of proteins. It is located on chromosome 3p21.31.

Especificidade

Anti-RhoA recognizes human RhoA.

Imunogênio

synthetic peptide corresponding to amino acids 177-189 located near the C-terminus of human RhoA.

Ações bioquímicas/fisiológicas

In multiciliated epithelial cells, RhoA (ras homolog family member A) controls the actin network dynamics. It also modulates membrane protrusion and contractility in the cell body. It is one of the essential factor for Ras transformation. It is associated with cancer metastasis.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Armazenamento e estabilidade

For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing, or storage in "frost-free" freezer, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours. For continuous use, store at 2-8°C for up to one month.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)