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R7753

Sigma-Aldrich

Rhapontin

≥99% (HPLC), from rhubarb

Sinônimo(s):

3,3′,5-Trihydroxy-4′-methoxystilbene 3-O-β-D-glucoside, NSC 43321, Rhaponticin

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About This Item

Fórmula empírica (Notação de Hill):
C21H24O9
Número CAS:
155-58-8
Peso molecular:
420.41
Número CE:
205-845-0
Número MDL:
MFCD00010117
Código UNSPSC:
12352201
ID de substância PubChem:
24899400

fonte biológica

rhubarb

Ensaio

≥99% (HPLC)

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

COc1ccc(\C=C\c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1O

InChI

1S/C21H24O9/c1-28-16-5-4-11(8-15(16)24)2-3-12-6-13(23)9-14(7-12)29-21-20(27)19(26)18(25)17(10-22)30-21/h2-9,17-27H,10H2,1H3/b3-2+/t17-,18-,19+,20-,21-/m1/s1

chave InChI

GKAJCVFOJGXVIA-DXKBKAGUSA-N

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Jeong-Keun Kim et al.
Journal of microbiology and biotechnology, 20(1), 82-87 (2010-02-06)
Biotransformation is often used to improve chemical activity. We evaluated the antimicrobial activity of rhapontigenin, converted from rhapontin after treatment with Pectinex. Rhapontigenin showed 4-16 times higher antimicrobial activity than rhapontin. Activity was higher against Gram positive strains than Gram
Yang Sun et al.
Journal of nanoscience and nanotechnology, 12(10), 7677-7684 (2013-02-21)
Rhaponticin (RA) extracted from many medicinal plants has been demonstrated to possess a variety of pharmacological activities including potent antitumor, antitumor-promoting, antithrombotic, antioxidant and vasorelaxant activities. However, its poor solubility and bioavailability restricted the clinical application greatly. In this work
Hyung Jun Lim et al.
Journal of colloid and interface science, 320(2), 460-468 (2008-02-12)
It is known that cyclodextrins (CDs) extract lipid components from bilayer of liposomes. This could undermine the potential benefits of liposomes as drug carriers. In this study, we demonstrated that PC-Chol liposomes with various CDs or rhapontin (Rh)-hydroxypropyl betaCD (HPbetaCD)
Fang-Fang Chen et al.
Journal of chromatography. A, 1252, 8-14 (2012-07-11)
The magnetic molecularly imprinted polymers (MMIPs) had been synthesized for the selective extraction and clean-up of rhaponticin in Chinese patent medicines (CPM). The MMIPs were prepared via suspension polymerization, using Fe(3)O(4) as magnetically component, rhaponticin as template molecule, acrylamide (AM)
Xuhua Liang et al.
Bioorganic & medicinal chemistry, 21(1), 178-185 (2012-11-28)
To improve the therapeutic effect of rhaponticin (RHA), a folate receptor (FR) targeted RHA conjugate was synthesized by utilizing a hydrophilic peptide spacer linked to folic acid (FA) via a releasable disulfide linker. This water-soluble conjugate was found to retain
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