PRS2125

Anti-MYD88 (ab1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-Myeloid differentiation primary response gene (88)
• Número MDL: MFCD04040473
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: predicted mol wt 35 kDa
• reatividade de espécies: human
• técnica(s): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• nº de adesão UniProt: U70451
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... MYD88(4615)

Descrição

Descrição geral

Myeloid differentiation primary response 88 (MYD88) is a cytosolic soluble adaptor protein. It possesses a toll-interleukin 1 receptor domain and a death domain. The gene encoding this protein is localized on human chromosome 3p22.2.

Imunogênio

a peptide corresponding to amino acids 233-248 of human MyD88, which differ from mouse by two amino acids.

Ações bioquímicas/fisiológicas

Myeloid differentiation primary response 88 (MYD88) activates innate immune response to Mycobacterium tuberculosis. It is an activator of nuclear factor κ B (NF-κB).The protein mediates the signaling pathways of toll-like and interleukin-1 receptors. Mutation in the gene encoding MYD88 is associated with diffuse large B-cell lymphoma.

Ligação

The action of this antibody can be blocked using blocking peptide SBP2125.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable