P6102

Anti-Potassium Channel K_ir2.1 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Sinônimo(s): Anti-ATFB9, Anti-HHBIRK1, Anti-HHIRK1, Anti-IRK1, Anti-KIR2.1, Anti-LQT7, Anti-SQT3
• Número MDL: MFCD02686542
• Código UNSPSC: 12352203
• NACRES: NA.41
• conjugado: unconjugated
• application: IHC; WB CL
• clone: polyclonal
• reatividade de espécies: rat
• citations: 5
• técnica(s): immunohistochemistry: suitable; western blot (chemiluminescent): 1:200

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: lyophilized powder
• reatividade de espécies: rat
• técnica(s): immunohistochemistry: suitable; western blot (chemiluminescent): 1:200
• nº de adesão UniProt: Q64273
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... KCNJ2(3759) ; mouse ... Kcnj2(16518) ; rat ... Kcnj2(29712)

Descrição

Descrição geral

Potassium voltage-gated channel subfamily J member 2 (KCNJ2) is an inward-rectifying potassium channel. This tetrameric protein possesses two transmembrane helix domains (M1 and M2), an ion-selective P-loop between M1 and M2 and cytoplasmic amino and carboxy-terminal domains. The gene encoding KCNJ2 is localized on human chromosome 17q24.3.

Imunogênio

synthetic peptide corresponding to amino acids 392-410 of human Kir2.1 (with additional N-terminal cysteine). This epitope is identical in rabbit, bovine, pig, and guinea pig and highly homologous in rat, mouse and chicken.

Ações bioquímicas/fisiológicas

Potassium voltage-gated channel subfamily J member 2 (KCNJ2) has been shown to have a role in the differentiation and proliferation of bone marrow-derived macrophages (BMDM) in mice. It allows the inward movement of K⁺ into the cell and maintains its balance. Mutations in the KCNJ2 gene have been linked to Andersen-Tawil syndrome.

forma física

Lyophilized from phosphate buffered saline, pH 7.4, 1% bovine serum albumin, and 0.025% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H312 + H332,H412
• Declarações de precaução: P261 - P271 - P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312
• Classificações de perigo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable