P4354

Monoclonal Anti-p19^INK4d antibody produced in mouse

clone DCS-100, ascites fluid

• Sinônimo(s): Anti-INK4D, Anti-p19, Anti-p19-INK4D
• Número MDL: MFCD01324442
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: ascites fluid
• tipo de produto de anticorpo: primary antibodies
• clone: DCS-100, monoclonal
• peso molecular: antigen 19 kDa
• contém: 15 mM sodium azide
• reatividade de espécies: human
• técnica(s): immunocytochemistry: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunoprecipitation (IP): suitable; microarray: suitable; western blot: 1:1,000 using a cultured human tumor cell line extract
• Isotipo: IgG1
• nº de adesão UniProt: P55273
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CDKN2D(1032)

Descrição

Descrição geral

Cyclin dependent kinase inhibitor 2D (CDKN2D), also referred to as p19INK4d, is part of the inhibitors of cyclin-dependent kinases (INK4) family. It consists of 166 amino acids and five ankyrin-like repeats that aid in protein-protein interactions. The gene encoding this protein is localized on human chromosome 19p13.

Especificidade

Shows no cross-reactivity with other closely related Cdk inhibitors, such as p15^INK4b, p16^INK4a and p18^INK4c.

Imunogênio

recombinant human p19^INK4d.

Aplicação

Monoclonal Anti-p19INK4d antibody produced in mouse has been used in microarray.

Ações bioquímicas/fisiológicas

Cyclin dependent kinase inhibitor 2D (CDKN2D) functions as a modulator of the cell cycle and has a role in DNA damage response. It acts as a chromatin accessibility factor. The protein associates with cyclin-dependent kinase 4 and 6 and inhibits their kinase activity.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable