P3493

Monoclonal Anti-Placenta Growth Factor-2 antibody produced in rat

clone 62526, purified immunoglobulin, lyophilized powder

• Sinônimo(s): Anti-PlGF-2
• Número MDL: MFCD02097209
• Código UNSPSC: 51111800
• NACRES: NA.41

Propriedades

• fonte biológica: rat
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 62526, monoclonal
• forma: lyophilized powder
• reatividade de espécies: mouse
• técnica(s): indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 1-2 μg/mL
• Isotipo: IgG2a
• nº de adesão UniProt: P49764
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: mouse ... Pgf(18654)

Descrição

Descrição geral

The antibody neutralizes receptor-ligand interaction. The antibody shows no cross-reactivity with recombinant human PlGF and recombinant human VEGF.

Imunogênio

purified recombinant mouse placenta growth factor 2 expressed in insect Sf 21 cells.

Ações bioquímicas/fisiológicas

Placental growth factors (PlGF) are involved in the growth, migration and survival of endothelial cells. All the four isoforms identified are expressed in placenta and umbilical vein endothelial cells. PlGF bind to specific Flt-1 receptors that result in activation and recruitment of dendritic cells, smooth muscle cells and inflammatory cells. PlGF2 has the ability to bind heparin while PlGF1 is a soluble isoform.

forma física

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline with 5% trehalose.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)