The PST-01 protease is a metalloprotease that has zinc ion at the active center and is very stable in the presence of water-soluble organic solvents. The reaction rates and the equilibrium yields of the aspartame precursor N-carbobenzoxy-L-aspartyl-L-phenylalanine methyl ester (Cbz-Asp-Phe-OMe)
Comparative biochemistry and physiology. Comparative physiology, 105(1), 79-83 (1993-05-01)
1. Programmed cell death proceeds by an unknown mechanism which results in characteristic morphological changes known as apoptosis. 2. We have proposed that, in hormone-induced apoptosis, cell death may be the result of an attack of cells destined to die
Biotechnology and bioengineering, 69(5), 577-583 (2000-07-18)
We recently demonstrated (J Am Chem Soc 121:3334-3340, 1999) that enzymatic enantioselectivity in organic solvents can be markedly enhanced by temporarily enlarging the substrate via salt formation. In the present study, this approach was expanded by finding that, in addition
Biotechnology and bioengineering, 64(6), 650-655 (1999-07-23)
Molecularly imprinted polymers are highly stable and can be sterilised, making them ideal for use in biotransformation process. In this communication, we describe a novel application of molecularly imprinted polymers in an enzymatic reaction. The enzymatic condensation of Z-L-aspartic acid
The journal of peptide research : official journal of the American Peptide Society, 63(4), 333-346 (2004-04-23)
Two cyclic analogs of vasopressin, -Pro-Arg-Gly-NH(2) (1) and -Pro-Arg-Gly-NH(2) (2) were synthesized by the solid phase method. Their structure was determined in aqueous solution by two-dimensional NMR techniques and simulated annealing algorithm from an extended template in X-PLOR. The total
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