This product meets 4X the minimum USP specifications. According to the USP monograph for Pancreatin, the 1X minimum specification is 25 USP units amylase, 2 USP units lipase, and 25 USP units protease per milligram. The calculated protease activity for the 4X preparation then, would be at least 100 units per milligram. This is a calculated value based on the USP monograph and are not reported separately on the Certificate of Analysis.
P1750
Pancreatina
4 × USP specifications
Sinônimo(s):
Pancreatina
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25 G
R$ 556,00
100 G
R$ 725,00
500 G
R$ 2.167,00
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25 G
R$ 556,00
100 G
R$ 725,00
500 G
R$ 2.167,00
About This Item
Agency
USP (specifications)
Formulário
powder
atividade específica
4 × USP specifications
contém
lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)
temperatura de armazenamento
−20°C
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Categorias relacionadas
Aplicação
Pancreatin from porcine pancreas has been used:
- for a study to assess the treatment of steatorrhea by lipase supplementation therapy[1]
- for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis[2]
- to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity [3]
- to assess cleavage by digestive enzymes.
- for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.[4]
- along with amyloglucosidase for the in vitro digestion of starch in food samples.[5]
Ações bioquímicas/fisiológicas
A pancreatina contém componentes enzimáticos, incluindo tripsina, amilase e lipase, ribonuclease e protease, produzidos pelas células exócrinas do pâncreas suíno. Esta combinação de enzimas permite hidrolisar proteínas, amido e gorduras. A pancreatina converterá no mínimo 25 vezes seu peso de amido de batata em carboidratos solúveis em 5 minutos em água a 40 °C, digerirá no mínimo 25 vezes o seu peso de caseína em 60 minutos em pH 7,5 a 40 °C e liberará, no mínimo, microequivalentes de ácido por min por mg de pancreatina de azeite de oliva em pH 9,0 a 37 °C.
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Certificados de análise (COA)
Lot/Batch Number
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Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
David C Whitcomb et al.
Digestive diseases and sciences, 52(1), 1-17 (2007-01-06)
A primary function of the pancreas is to produce digestive enzymes that are delivered to the small intestine for the hydrolysis of complex nutrients. Much of our understanding of digestive enzymes comes from studies in animals. New technologies and the
Muhammad Awais et al.
Foods (Basel, Switzerland), 9(5) (2020-05-28)
The changes in structure and digestion properties of mung bean starch due to hydrothermal treatment at various controlled temperatures were investigated. Results showed the increase in onset temperature (To) from 66.33 °C to 76.69 °C and decrease in enthalpies (∆Hg
Gabriele Rocchetti et al.
Antioxidants (Basel, Switzerland), 9(4) (2020-04-10)
In this work, different commercial extra-virgin olive oils (EVOO) were subjected to in vitro gastrointestinal digestion and the changes in bioactive compounds were evaluated by ultra-high-pressure liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry, using untargeted metabolomics. As expected, raw EVOO
Asavela Ngalavu et al.
Animals : an open access journal from MDPI, 10(4) (2020-04-17)
Feed fiber composition is usually considered as one of the factors that have an impact on digestive tract microbiota composition. The investigations on the level of fermentation and in-vitro digestibility of different fibers are not well understood. The aim of
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units of pancreatin cas number 8049-47-6
1 answer-
Helpful?
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What is the trypsin activity of this P1750 product ?
1 answer-
This product is not specifically tested for trypsin activity. The material meets USP requirements. This monograph includes testing for protease, amylase, and lipase.
Helpful?
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What is the solubility of p1750 pancreatin in water?
1 answer-
This product is soluble at 7 mg/mL in water and may yield a hazy solution.
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As per USP: Pancreatin contains, in each mg, not less than 25 USP Units of protease activity. I assume that product P1750 contains minimum 100 USP units of protease activity in each mg. What is the maximum USP units of protease activity in P1750 ?
1 answer-
Yes, this is correct. To meet the USP specifications, the protease activity will be less than 100 USP Units/mg.
Helpful?
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