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O5501

Sigma-Aldrich

Oxyphenonium bromide

Sinônimo(s):

2-([Cyclohexylhydroxyphenylacetyl]oxy)-N,N-diethyl-N-methylethanaminium bromide

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About This Item

Fórmula linear:
C21H34NO3Br
Número CAS:
50-10-2
Peso molecular:
428.40
Número CE:
200-010-7
Número MDL:
MFCD00050259
Código UNSPSC:
12161900
ID de substância PubChem:
24898019

descrição

cationic

Ensaio

>98% (TLC)

peso molecular

428.40 g/mol

cadeia de caracteres SMILES

Br.CC[N](C)(CC)CCOC(=O)C(O)(C1CCCCC1)c2ccccc2

InChI

1S/C21H34NO3.BrH/c1-4-22(3,5-2)16-17-25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6,8-9,12-13,19,24H,4-5,7,10-11,14-17H2,1-3H3;1H

chave InChI

JKJFWDDPBNHJPV-UHFFFAOYSA-N

Aplicação

Oxyphenonium bromide has been used in a study to assess masking mechanisms of bitter taste of drugs. [1] It has also been used in a study to investigate stoichiometric and microenvironmental effects on hydrolysis of propantheline in cyclodextrin solutions. [2]

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302 + H312 + H332

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
044F0691

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G I Nezhinskaya et al.
Bulletin of experimental biology and medicine, 145(1), 55-57 (2008-11-26)
Blood plasma proteins modulated the effects of muscarinic receptor antagonist methacin. Administration of methacin in combination with albumin or C-reactive protein (but not with IgG) abolished the broncholytic effect of methacin. It was probably associated with allosteric antagonism to M2
T P Berezina et al.
Bulletin of experimental biology and medicine, 147(3), 296-300 (2009-06-17)
Psychogenic stress in rabbits (fixation to a frame) was accompanied by the inhibition of contractile activity of the gastric antrum and pylorus. These changes persisted during blockade of muscarinic receptors, nicotinic receptors, alpha(2)-adrenoceptors, and beta(1)/beta(2) adrenoceptors. A stress-induced decrease in
V A Kozhevnikov et al.
Anesteziologiia i reanimatologiia, (5)(5), 15-19 (2006-12-23)
The good tolerability of sevoflurane, the mild and prompt onset of a hypnotic state, the absence of airway irritation, and the safe use of the agent make the anesthetic of choice for introductory anesthesia in pediatric cardiosurgery. The purpose of
N Funasaki et al.
Journal of pharmaceutical sciences, 90(6), 740-748 (2001-05-18)
The effects of alpha-, beta-, and gamma-cyclodextrins (CDs) on the basic hydrolysis of propantheline bromide (PB) and oxyphenonium bromide (OB) are analyzed in terms of the stoichiometry and microenvironments of their complexes. The rate constant of each species is evaluated
T Joseph et al.
Arzneimittel-Forschung, 47(7), 869-872 (1997-07-01)
The effect of a combination of 150 mg tinidazole (CAS 19387-91-8) and 1 mg oxyphenonium bromide (CAS 50-10-2), referred to as the combination, was examined in various animal species to assess its safety. In mice and rats, the combination in
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