N214

Neutrophil Activating Peptide-2 human

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Sinônimo(s): NAP-2
• Número MDL: MFCD00241917
• Código UNSPSC: 51111800

Propriedades

• fonte biológica: human
• recombinante: expressed in E. coli
• Ensaio: >97% (SDS-PAGE)
• forma: lyophilized powder
• potência: 0.1-0.3 μg/mL ED₅₀ (cytochalasin B treated human neutrophils); 0.1-0.5 ng/mL ED₅₀ (BaF/3 hCXCR-2 transfected cells)
• peso molecular: ~7.6 kDa
• condição de armazenamento: avoid repeated freeze/thaw cycles (Storage in "frost-free" freezers is not recommended)
• técnica(s): cell culture | mammalian: suitable
• Impurezas: endotoxin, tested
• nº de adesão UniProt: P02775
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... PPBP(5473)

Descrição

Ações bioquímicas/fisiológicas

Neutrophil Activating Peptide-2, a member of the CXC chemokine family, chemoattracts and activates neutrophils and also binds CXCR-2. NAP-2 is proteolytically processed C-terminal fragments of platelet basic protein (PBP), which is found in the α-granules of human platelets.

forma física

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.

Nota de análise

The biological activity is measured by the induction of myeloperoxidase release from cytochalasin B treated human neutrophils.