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N1134

Sigma-Aldrich

Se-(p-Nitrobenzyl)-6-selenoinosine

≥95%

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About This Item

Fórmula linear:
C17H17SeN5O6
Número CAS:
40144-12-5
Peso molecular:
466.31
Número MDL:
MFCD00056966
Código UNSPSC:
41106305
ID de substância PubChem:
24897462

Ensaio

≥95%

forma

solid

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OCC1OC(C(O)C1O)n2cnc3c([Se]Cc4ccc(cc4)N(=O)=O)ncnc23

InChI

1S/C17H17N5O6Se/c23-5-11-13(24)14(25)17(28-11)21-8-20-12-15(21)18-7-19-16(12)29-6-9-1-3-10(4-2-9)22(26)27/h1-4,7-8,11,13-14,17,23-25H,5-6H2

chave InChI

XCNANXPIYMOXKW-UHFFFAOYSA-N

Ações bioquímicas/fisiológicas

Se-(p-nitrobenzyl)-6-selenoinosine is a selenium containing inosine derivative that may have activities similar to S-(p-nitrobenzyl)-6-thioinosine (NBTI), an inhibitor of adenosine equilibrative transporters.

Palavra indicadora

Danger

Frases de perigo

H301 + H331,H373,H410

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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M A Timóteo et al.
Neurochemistry international, 52(4-5), 834-845 (2007-11-21)
The influence of nerve stimulation pattern on transmitter release inhibition by L-citrulline, the co-product of NO biosynthesis by nitric oxide synthase (NOS), was studied in the rat phrenic nerve-hemidiaphragm. We also investigated the putative interactions between NOS pathway and the
Sílvia V Conde et al.
Journal of neurochemistry, 89(5), 1148-1156 (2004-05-19)
The effect of hypoxia on the release of adenosine was studied in vitro in the rat whole carotid body (CB) and compared with the effect of hypoxia (2%, 5% and 10% O(2)) on adenosine concentrations in superior cervical ganglia (SCG)
Alexandre dos Santos-Rodrigues et al.
Biochemical and biophysical research communications, 414(1), 175-180 (2011-09-29)
Adenosine is an important modulator of neuronal survival and differentiation in the CNS. Our previous work showed that nucleoside transporters (NTs) are present in cultures of chick retinal cells, but little is known about the mechanisms regulating adenosine transport in
Laura Oliveira et al.
Neuroscience letters, 459(3), 127-131 (2009-05-12)
At the rat motor nerve terminals, activation of muscarinic M(1) receptors negatively modulates the activity of inhibitory muscarinic M(2) receptors. The present work was designed to investigate if the negative crosstalk between muscarinic M(1) and M(2) autoreceptors involved endogenous adenosine

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