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Documentos Principais

M8945

Sigma-Aldrich

Matrix Metalloproteinase-9 human

recombinant, >90% (SDS-PAGE), buffered aqueous solution

Sinônimo(s):

Gelantinase-B, Gelatinase, 95 kDa, MMP-9

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10 μG
R$ 6.573,00

R$ 6.573,00


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10 μG
R$ 6.573,00

About This Item

Número MDL:
Código UNSPSC:
12352204
NACRES:
NA.32

R$ 6.573,00


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Nível de qualidade

Ensaio

>90% (SDS-PAGE)

Formulário

buffered aqueous solution

peso molecular

apparent mol wt ~93 kDa

nº de adesão UniProt

Condições de expedição

dry ice

temperatura de armazenamento

−70°C

Informações sobre genes

human ... MMP9(4318)

Ações bioquímicas/fisiológicas

MMP-9 degrades the collagens that make up the extracellular matrix, which has a role in the control of angiogenesis.

forma física

Solution in Tris-HCl, pH 7.5, Calcium Chloride, Sodium Chloride, and Brij-35

Nota de análise

The biological activity is measured by its ability to cleave a fluorogenic peptide substrate.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Carla Graça et al.
Foods (Basel, Switzerland), 9(10) (2020-10-07)
The influence of flour replacement by yogurt or curd-cheese additions (from 10% to 20%, w/w) on the glycemic response and bioactivity improvements of gluten-free bread was evaluated. Starch digestibility, measured by an in vitro digestion model, was applied to determine
Gelatinase B
Collier, I.E., and Goldberg, G.I. et al.
Handbook of Proteolytic Enzymes, 1205-1210 (1998)
S Chandler et al.
Neuroscience letters, 201(3), 223-226 (1995-12-15)
Matrix metalloproteinases (MMPs) are a group of enzymes responsible for the degradation of interstitial connective tissue and basement membrane. The coding sequences for five of the human MMPs, viz. interstitial collagenase, 72 kDa gelatinase, stromelysin-1, matrilysin and 92 kDa gelatinase
Tomoaki Fukui et al.
Biochemical and biophysical research communications, 460(3), 741-746 (2015-03-31)
Non-destructive detection of cartilage-degrading activities represents an advance in osteoarthritis (OA) research, with implications in studies of OA pathogenesis, progression, and intervention strategies. Matrix metalloproteinases (MMPs) are principal cartilage degrading enzymes that contribute to OA pathogenesis. MMPSense750 is an in-vivo
Narjes Khatoun Shabani Sadr et al.
Biochemical genetics, 58(6), 883-900 (2020-07-02)
Sialic acid (N-acetylneuraminic acid, NANA) is found at all cell surfaces of vertebrates. Although it is widely accepted that sialic acid is an essential substrate for brain development via a significant role in nerve transfers, structure of glycosides, and synaptogenesis

Questions

1–4 of 4 Questions  
  1. What is the molecular weight of product M8945 (Matrix Metalloproteinase-9 Human)

    1 answer
    1. Human MMP-9 consists of a 688 amino acid residue recombinant protein which has a predicted molecular mass of approximately 77 kDa. By SDS-PAGE the apparent molecular mass is approximately 93 kDa.

      Helpful?

  2. Is product M8945 (Marix Metalloproteinase-9 Human) endotoxin free?

    1 answer
    1. This product contains < 1.0 EU/ug of the enzyme.

      Helpful?

  3. Does product M8945 (Matrix Metalloproteinase-9 Human) need to be activated?

    1 answer
    1. To activate recombinant human MMP-9, prepare a p-aminophenylmercuric acetate (APMA) solution in DMSO. Add the AMPA solution to the MMP-9 to a final APMA concentration of 1 mM. Incubate at 37°C. for 16 - 24 hours.

      Helpful?

  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

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