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M2776

Sigma-Aldrich

Methylergonovine maleate salt

≥98% (TLC)

Sinônimo(s):

9,10-Didehydro-N-[(S)-1-(hydroxymethyl)propyl]-6-methylergoline-8β-carboxamide maleate salt, Methergine maleate salt

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About This Item

Fórmula empírica (Notação de Hill):
C20H25N3O2 · C4H4O4
Número CAS:
Peso molecular:
455.50
Número CE:
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:

Ensaio

≥98% (TLC)

cor

white

solubilidade

H2O: 25 mg/mL
0.1 M HCl: soluble
ethanol: slightly soluble

cadeia de caracteres SMILES

[H]\C(=C(/[H])C(O)=O)C(O)=O.[H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N[C@@H](CC)CO)c34

InChI

1S/C20H25N3O2.C4H4O4/c1-3-14(11-24)22-20(25)13-7-16-15-5-4-6-17-19(15)12(9-21-17)8-18(16)23(2)10-13;5-3(6)1-2-4(7)8/h4-7,9,13-14,18,21,24H,3,8,10-11H2,1-2H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t13-,14+,18-;/m1./s1

chave InChI

NOFOWWRHEPHDCY-DAUURJMHSA-N

Informações sobre genes

Procurando produtos similares? Visita Guia de comparação de produtos

Ações bioquímicas/fisiológicas

Ergot alkaloid which interacts with serotonergic, dopaminergic and α-adrenergic systems. Dopamine antagonist.

Pictogramas

Skull and crossbonesHealth hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Repr. 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Ahmet Yagmur Bas et al.
European journal of pediatrics, 170(5), 633-637 (2010-10-26)
Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country hospital in Turkey and developed sepsis-like symptoms and encephalopathy within
Tomoko Ishibashi et al.
Journal of anesthesia, 25(3), 405-408 (2011-03-25)
Neurological deficits associated with methylergometrine have been reported primarily as a result of reversible cerebral vasoconstriction syndromes (RCVS). RCVS are characterized by reversible multifocal vasoconstrictions of the cerebral arteries heralded by acute severe headache with or without neurological deficits. Here
Late onset of coronary vasospasm after administration of methyl-ergometrine for gynecologic bleeding.
Francesco Santoro et al.
International journal of cardiology, 161(2), e29-e30 (2012-04-21)
Taro Nonaka et al.
Obstetrics and gynecology, 117(2 Pt 2), 452-455 (2011-01-22)
Uterine arteriovenous malformations are a rare and potentially life-threatening condition. Medical therapy has not been popular because of the propensity for excessive bleeding in the patient. As a result, the effect of gonadotropin-releasing hormone (Gn-RH) agonists on uterine arteriovenous malformations
F Aboukhoudir et al.
Annales de cardiologie et d'angeiologie, 61(5), 311-316 (2012-09-11)
To assess the prevalence of coronary artery spasm during dobutamine stress chocardiography (DSE), to describe clinical and echocardiographic characteristics and prognosis. We evaluated all the patients with known or suspected coronary artery disease (CAD) referred to our echocardiography laboratory for

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