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M0814

Sigma-Aldrich

R(−)-Me5 hydriodide

solid

Sinônimo(s):

1-(2,6-Dimethylphenoxy)-3-methyl-2-butanamine hydriodide

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About This Item

Fórmula empírica (Notação de Hill):
C13H21NO · HI
Peso molecular:
335.22
Número MDL:
MFCD03452961
Código UNSPSC:
12352200
ID de substância PubChem:
24278531

forma

solid

cor

white

solubilidade

H2O: 22 mg/mL

cadeia de caracteres SMILES

I[H].CC(C)C(N)COc1c(C)cccc1C

InChI

1S/C13H21NO.HI/c1-9(2)12(14)8-15-13-10(3)6-5-7-11(13)4;/h5-7,9,12H,8,14H2,1-4H3;1H

chave InChI

AQLAXCGHPBMFIJ-UHFFFAOYSA-N

Informações sobre genes

human ... SCN2A(6326)

Aplicação

May be used as a sodium channel blocker in sketetal muscle.

Ações bioquímicas/fisiológicas

Potent sodium channel antagonist.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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M Takanashi et al.
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Pulmonary surfactant is a complex mixture of phospholipids and four surfactant-associated proteins (SP-A, SP-B, SP-C and SP-D). The biological functions of SP-A and SP-D are primarily twofold, namely surfactant homeostasis and host defense. The hydrophobic surfactant proteins, SP-B and SP-C
A De Luca et al.
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On the basis of the information about drug receptor on voltage-gated sodium channels, mexiletine (Mex) analogs with substitutions at either the asymmetric carbon atom or the aromatic ring were synthesized as pure enantiomers. The compounds were tested in vitro for
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Bladder pain syndrome/interstitial cystitis (BPS/IC), diagnosed according to the new 2008 criteria of the European Society for the Study of Interstitial Cystitis (ESSIC), may lead to detrusor fibrosis. In some inflammatory diseases, fibrosis is related to YKL-40. The aims were
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