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I8885

Sigma-Aldrich

Anti-Human IgG (Fc specific) antibody produced in goat

whole antiserum

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

fonte biológica

goat

conjugado

unconjugated

forma do anticorpo

whole antiserum

tipo de produto de anticorpo

secondary antibodies

clone

polyclonal

contém

15 mM sodium azide

técnica(s)

indirect ELISA: 1:50,000
quantitative precipitin assay: 4.0-7.0 mg/mL

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

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Descrição geral

Immunoglobulin G (IgG), a widely expressed serum antibody, has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein, usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG.

Especificidade

Specificity for the Fc fragment of human IgG is determined by immunoelectrophoresis (IEP) versus normal human serum and Fc fragment of human IgG. No reactivity is observed versus purified human IgA, IgG (Fab fragment), IgM, Bence Jones kappa and Bence Jones lambda myeloma proteins.

Aplicação

Anti-Human IgG (Fc specific) antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA).

Ações bioquímicas/fisiológicas

Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

forma física

Goat Anti-Human IgG is supplied as a liquid containing 0.1% sodium azide (see MSDS) as a preservative.

Armazenamento e estabilidade

For continuous use, store at 2-8°C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. This goat antiserum was maintained at pH 5.0 for 40 minutes to meet U.S.D.A. requirements.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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