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H7898

Sigma-Aldrich

15(S)-Hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoic acid

~100 μg/mL in ethanol, ~98%

Sinônimo(s):

15(S)-HEPE

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About This Item

Fórmula empírica (Notação de Hill):
C20H30O3
Número CAS:
86282-92-0
Peso molecular:
318.45
Número MDL:
MFCD00065817
Código UNSPSC:
12352211
ID de substância PubChem:
24895813

Ensaio

~98%

forma

liquid

concentração

~100 μg/mL in ethanol

grupo funcional

carboxylic acid

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC\C=C/C[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(O)=O

InChI

1S/C20H30O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h3-5,8-11,13-14,17,19,21H,2,6-7,12,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,13-3-,17-14+/t19-/m0/s1

chave InChI

WLKCSMCLEKGITB-DBVSHIMFSA-N

Embalagem

Packaged under Argon.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Hiroyasu Inoue
Nihon rinsho. Japanese journal of clinical medicine, 63(4), 578-583 (2005-04-15)
Peroxisome proliferator-activated receptors (PPARs), a family of three nuclear receptors/transcription factors, are widely recognized as molecular targets for drugs against lifestyle related disease. In spite of intensive search for natural ligands, no truly endogenous ligand has been identified as yet.
John Climax et al.
Journal of the American Heart Association, 9(16), e016334-e016334 (2020-08-12)
Background Epeleuton is 15-hydroxy eicosapentaenoic acid ethyl ester, a second-generation synthetic n-3 fatty acid derivative of eicosapentaenoic acid. The primary objective was to assess the effect of epeleuton on markers of nonalcoholic fatty liver disease (NAFLD) with post hoc analyses
C Miller et al.
Lipids, 24(12), 998-1003 (1989-12-01)
Clinical studies have indicated that dietary fish oil may have therapeutic value in the treatment of psoriasis, a hyperproliferative, inflammatory skin disorder characterized by elevated LTB4. To evolve a possible mechanism for these beneficial effects, we determined the metabolic fate
Aude Le Bail et al.
BMC molecular biology, 9, 75-75 (2008-08-20)
Brown algae are plant multi-cellular organisms occupying most of the world coasts and are essential actors in the constitution of ecological niches at the shoreline. Ectocarpus siliculosus is an emerging model for brown algal research. Its genome has been sequenced
Nguyen Dang Hung et al.
British journal of pharmacology, 162(5), 1119-1135 (2010-11-26)
Lysophosphatidylcholines (lysoPCs) with polyunsaturated acyl chains are known to exert anti-inflammatory actions. 15-Lipoxygeanation is crucial for anti-inflammatory action of polyunsaturated acylated lysoPCs. Here, the anti-inflammatory actions of 1-(15-hydroxyeicosapentaenoyl)-lysoPC (15-HEPE-lysoPC) and its derivatives were examined in a mechanistic analysis. Anti-inflammatory actions
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