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H4525

Sigma-Aldrich

19-Hydroxytestosterone

≥98% (HPLC)

Sinônimo(s):

4-Androstene-17β,19-diol-3-one

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About This Item

Fórmula empírica (Notação de Hill):
C19H28O3
Número CAS:
2126-37-6
Peso molecular:
304.42
Número MDL:
MFCD00198776
Código UNSPSC:
12352200

Ensaio

≥98% (HPLC)

controle de medicamentos

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

cadeia de caracteres SMILES

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34CO)[C@@H]1CC[C@@H]2O

Pictogramas

Health hazardExclamation mark
GHS08,GHS07

Palavra indicadora

Warning

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Repr. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análise (COA)

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S Watanabe et al.
Endocrine journal, 41(4), 421-427 (1994-08-01)
19-Hydroxyandrogens are known to be an intermediary metabolite in the aromatizing reaction, though the physiological role of this compound has not yet been clarified. In this study, microsomes obtained from human corpus luteum were incubated with testosterone or 19-hydroxytestosterone (19-OHT)
P A Cole et al.
The Biochemical journal, 268(3), 553-561 (1990-06-15)
Aromatase is a cytochrome P-450 enzyme that catalyzes the conversion of androgens into oestrogens via sequential oxidations at the 19-methyl group. Despite intensive investigation, the mechanism of the third step, conversion of the 19-aldehydes into oestrogens, has remained unsolved. We
Y S Moon et al.
Steroids, 39(4), 419-430 (1982-04-01)
In eight separate experiments, theca and granulosa were isolated from human follicles (5-25 mm in diameter), and their capacities to metabolize radiolabelled testosterone in 24 hour cultures were assessed. Theca metabolized testosterone primarily to androstenedione, however significant aromatization to estradiol-17
G Leschber et al.
Andrologia, 21(6), 529-534 (1989-11-01)
Subcutaneous treatment of immature male rats with an estrogen precursor, 19-hydroxy-testosterone (19-OHT), at a daily dose of 1 mg/animal for 14 days leads to a significant decrease in the weight of testis, ventral prostate and seminal vesicle. The peripheral levels
J I Raeside et al.
The Journal of endocrinology, 137(2), 281-289 (1993-05-01)
19-Hydroxytestosterone and 19-hydroxyandrostenedione have been identified as secretory products of the testes in the mature male domestic pig. Their isolation and identification were made by reverse-phase high-performance liquid chromatography and capillary gas chromatography-mass spectrometry (CGC-MS) of extracts from testicular vein

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