H1791

Anti-HOXC8 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-HOX3A, Anti-Homeobox 3A, Anti-Homeobox C8, Anti-Hox-3.1 (mouse)
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen ~34 kDa
• reatividade de espécies: human
• concentração: ~1.0 mg/mL
• técnica(s): immunoprecipitation (IP): 2.5-5 μg using lysates of HEK-293T cells over expressing human HOXC8; western blot: 1-2 μg/mL using extracts of HEK-293T cells over expressing human HOXC8
• nº de adesão UniProt: P31273
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... HOXC8(3224) ; mouse ... Hoxc8(15426) ; rat ... Hoxc8(24460)

Descrição

Descrição geral

Homeobox C8 (HOXC8) is a member of homeobox (HOX) family. It is a transcription factor, expressed in neural tube, brain, breast and adult bone marrow. HOX genes consist of a highly conserved 60-amino-acid region (the homeobox) with DNA-binding activity, that contributes to their activity as transcription factors. The gene is located on human chromosome 12q13.

Imunogênio

synthetic peptide corresponding to amino acids 96-110 of human HOXC8 conjugated to KLH. The corresponding sequence is identical in mouse and rat.

Aplicação

Anti-HOXC8 antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.

Ações bioquímicas/fisiológicas

Homeobox C8 (HOXC8) is involved in cell growth, migration and metastasis of various cancers. Hox genes are important for embryonic development. Mutations in this gene are implicated in the development of cancers, such as leukemias or neoplasms of the breast, prostate, kidney, colon, skin and brain.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.