GW22683

Anti-ENO1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: chicken
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: human, mouse, rat
• fabricante/nome comercial: Genway 15-288-22683
• técnica(s): western blot: suitable
• nº de adesão NCBI: NP_001419.1
• nº de adesão UniProt: P06733
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... ENO1(2023)

Descrição

Descrição geral

Enolase 1 (ENO1 or ENOα) is a type of enolase enzyme, which in mammals, has three different isoforms namely, α-, β- and γ-enolase. It is an essential cytoplasmic glycolytic enzyme, and has a molecular weight of 48kDa. An alternatively spliced form resides in the nucleus, which has a molecular weight of 37kDa.[1]

Imunogênio

Immunogen Sequence: GI # 4503571, sequence 161-320

Recombinant enolase 1

Aplicação

Anti-ENO1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Ações bioquímicas/fisiológicas

Enolase 1(α-enolase) is a homodimer composed of 2 α subunits. ENO1 is involved in tumor progression and prognosis of human glioma. Overexpression of ENO1 is associated with progression of glioma while its knockdown leads to suppressed cell growth, migration and invasion progression by inactivating the PI3K/Akt pathway in glioma cells.[1] The lower expression of ENO1 decreases the response to hypoxia and enhances the sensitivity of the cells to radiation therapy. It may act as a drug target for the treatment of breast cancer.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)