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Documentos Principais

G6646

Sigma-Aldrich

Growth Hormone Releasing Factor rat

≥95% (HPLC), powder, synthetic

Sinônimo(s):

GRF

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About This Item

Fórmula empírica (Notação de Hill):
C225H361N77O66S
Número CAS:
Peso molecular:
5232.82
Número MDL:
Código UNSPSC:
12352200

fonte biológica

synthetic

Ensaio

≥95% (HPLC)

Formulário

powder

composição

Peptide content, ~70%

nº de adesão UniProt

temperatura de armazenamento

−20°C

chave InChI

ORNDKVCWLUZAQL-FOWIMTFFSA-N

Informações sobre genes

rat ... Ghrh(29446)

Amino Acid Sequence

His-Ala-Asp-Ala-Ile-Phe-Thr-Ser-Ser-Tyr-Arg-Arg-Ile-Leu-Gly-Gln-Leu-Tyr-Ala-Arg-Lys-Leu-Leu-His-Glu-Ile-Met-Asn-Arg-Gln-Gln-Gly-Glu-Arg-Asn-Gln-Glu-Gln-Arg-Ser-Arg-Phe-Asn

Ações bioquímicas/fisiológicas

Hypothalamic peptide that stimulates release of somatotropin from anterior pituitary

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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T Audhya et al.
Proceedings of the National Academy of Sciences of the United States of America, 82(9), 2970-2974 (1985-05-01)
Polyclonal antibodies to synthetic human pancreatic growth hormone-releasing factor [hpGRF(1-44)NH2] and rat hypothalamic growth hormone-releasing factor [rhGRF(1-43)OH] were produced in rabbits by injecting these weak immunogens, coupled to thyroglobulin and emulsified with complete Freund's adjuvant in the presence of activated
N Deslauriers et al.
Regulatory peptides, 20(3), 261-271 (1988-03-01)
We studied the effect of rat growth hormone-releasing factor-(1-43) acid, rGRF(1-43)OH, on the long-term secretion of rat growth hormone (rGH) in dispersed primary cultured cells of rat anterior pituitaries over a period of 7 days or longer. Results of the
J Kraicer et al.
Canadian journal of physiology and pharmacology, 69(2), 181-184 (1991-02-01)
The purpose of this study was to characterize the biological activity of the synthetic rat growth hormone releasing factor analogue rGRF(1-29)NH2 and to compare its action on growth hormone (GH) release to that of authentic rGRF(1-43)OH. We first compared the
L G Frigeri et al.
Endocrinology, 122(6), 2940-2945 (1988-06-01)
Treatment of obese yellow Avy/A mice with the human GH (hGH) peptide hGH-(1-43) enhanced the in vitro sensitivity of their adipose tissue to insulin. Insulin-stimulated glucose oxidation, as determined by measurement of 14CO2 production, was enhanced 106% after administration of
J Spiess et al.
Nature, 303(5917), 532-535 (1983-06-09)
The importance of the hypothalamus in the regulation of growth hormone (GH) secretion from the adenohypophysis has been supported by experimental and clinical evidence. It has been observed that GH secretion is in part controlled by hypothalamic GH release-inhibiting factors

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