D7071

Dapoxetine hydrochloride

≥98% (HPLC)

• Sinônimo(s): (S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride, S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride
• Fórmula empírica (Notação de Hill): C₂₁H₂₃NO · HCl
• Número CAS: 129938-20-1
• Peso molecular: 341.87
• Número MDL: MFCD08272809
• Código UNSPSC: 12352200
• ID de substância PubChem: 329798842
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• forma: powder
• atividade óptica: [α]/D +125 to +135°, c = 1 in methanol
• condição de armazenamento: desiccated
• cor: white
• solubilidade: DMSO: ≥20 mg/mL
• originador: Eli Lilly
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: Cl.CN(C)[C@@H](CCOc1cccc2ccccc12)c3ccccc3
• InChI: 1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1
• chave InChI: IHWDIQRWYNMKFM-BDQAORGHSA-N
• Informações sobre genes: human ... SLC6A4(6532)

Descrição

Descrição geral

Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.

Ações bioquímicas/fisiológicas

Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe.

Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation

Características e benefícios

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302,H319,H413
• Declarações de precaução: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Classificações de perigo: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable