D4876

Dextrana

average mol wt 150,000

• Fórmula linear: (C₆H₁₀O₅)_n
• Número CAS: 9004-54-0
• UNSPSC Code: 12352201
• NACRES: NA.25
• EC Number: 232-677-5
• MDL number: MFCD00130935

Propriedades

• biological source: bacterial (Leuconostoc mesenteroides)
• Quality Segment: 200
• form: powder
• optical activity: [α]/D 199°
• mol wt: average mol wt 150,000
• color: white
• solubility: H₂O: soluble 20 mg/mL
• SMILES string: O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O
• InChI: 1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
• InChI key: FZWBNHMXJMCXLU-UHFFFAOYSA-N

Descrição

Application

O uso de dextranas como braços espaçadores longos e hidrofílicos melhora o desempenho das proteínas imobilizadas que agem sobre macromoléculas.

Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants and physical structure components.[1] Dextrans may be used as long hydrophilic spacer arms to improve the performance (freedom of movement) of conjugated/bound proteins. Dextrans may be derivatized for use in biosensor systems.[2] Dextran 150 may be used to study iron delivery to cells, cell membrane permeabilization and red blood cell aggregation.

Preparation Note

With the exception of the highest MW dextran, D5501 (MW range = 5 million to 40 million), dextrans are very water soluble. Sigma tests the solubility of dextrans at concentrations generally exceeding 30 mg/ml in water. Dextrans are also freely soluble in DMSO, formamide, ethylene glycol, and glycerol. Neutral-aqueous dextran solutions can be sterilized by autoclaving at 110-115^oC for 30 to 45 minutes. Dextran can be hydrolyzed by strong acids at high temperatures. The terminal reducing end group of dextran can be oxidized in alkaline solutions.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Informações de segurança

• Classe de armazenamento: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)