Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

Visualizar Toda a Documentação

C9415

Sigma-Aldrich

Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Nε-Boc-Lys methyl ester

≥85% (HPLC)

Sinônimo(s):

CGP-29287

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula empírica (Notação de Hill):
C72H110N20O15
Número CAS:
93287-54-8
Peso molecular:
1495.77
Número MDL:
MFCD00133577
Código UNSPSC:
12352200
ID de substância PubChem:
329775207

Ensaio

≥85% (HPLC)

forma

solid

técnica(s)

ligand binding assay: suitable

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC[C@H](C)[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)OCc4ccccc4)C(=O)N[C@@H](Cc5c[nH]cn5)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC

InChI

1S/C72H110N20O15/c1-9-44(4)59(65(100)89-55(36-48-39-78-42-83-48)62(97)85-51(67(102)105-8)25-16-17-29-81-70(103)107-72(5,6)7)91-58(94)37-57(93)52(33-43(2)3)86-63(98)54(35-47-38-77-41-82-47)87-61(96)53(34-45-21-12-10-13-22-45)88-64(99)56-28-20-32-92(56)66(101)50(27-19-31-80-69(75)76)84-60(95)49(26-18-30-79-68(73)74)90-71(104)106-40-46-23-14-11-15-24-46/h10-15,21-24,38-39,41-44,49-57,59,93H,9,16-20,25-37,40H2,1-8H3,(H,77,82)(H,78,83)(H,81,103)(H,84,95)(H,85,97)(H,86,98)(H,87,96)(H,88,99)(H,89,100)(H,90,104)(H,91,94)(H4,73,74,79)(H4,75,76,80)/t44-,49-,50-,51-,52-,53-,54-,55-,56-,57-,59-/m0/s1

chave InChI

DLAHCJHYEAZDLE-VRYQDWSQSA-N

Ações bioquímicas/fisiológicas

Primate-specific renin inhibitor with prolonged duration of action.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

J M Wood et al.
Clinical and experimental hypertension. Part A, Theory and practice, 9(2-3), 337-343 (1987-01-01)
The primate-specific renin inhibitor CGP 29287 (30 mg/kg/d, n = 5) or the converting-enzyme inhibitor CGS 14831 (30 mg/kg/d, n = 8) were administered by continuous intraperitoneal infusion via osmotic minipumps to normotensive marmosets fed a low salt diet. CGP
J M Wood et al.
Journal of hypertension, 7(8), 615-618 (1989-08-01)
The renin inhibitor CGP 29,287 was administered continuously for 7 days (30 mg/kg per day, intraperitoneally, via osmotic minipumps) to normotensive marmosets fed a low-salt diet. As a control, another group of marmosets was given vehicle only. After 7 days
K G Hofbauer et al.
Journal of cardiovascular pharmacology, 7 Suppl 4, S62-S68 (1985-01-01)
The hypotensive effects of inhibitors of renin or converting-enzyme (CE) were compared in normotensive sodium-depleted marmosets. Renin was inhibited by an antiserum or a monoclonal antibody against human kidney renin or by peptidic renin inhibitors. The fall in blood pressure
U Humke et al.
The American journal of physiology, 261(1 Pt 2), F179-F186 (1991-07-01)
A method for the measurement of renal clearances was adapted in a novel manner to the conscious marmoset. Twenty-four hours before an experiment, animals underwent surgery for placement of both femoral arterial and venous catheters. A catheter was also implanted
D Neisius et al.
The American journal of physiology, 251(5 Pt 2), H897-H902 (1986-11-01)
The relative importance of angiotensin II for the renal vasodilatory response after converting-enzyme inhibition was evaluated by a comparison of the effects of converting-enzyme and renin inhibition on renal vascular resistance. Renal, mesenteric, and hindquarter blood flows were measured with
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica