C7493

Aminopurinyl pyranobenzopyranone monohydrate

≥98% (HPLC), solid

• Sinônimo(s): (5aS,7S)-7-[2-(6-Amino-3H-purin-3-yl)-1-methylethyl]-5a,6,8,9-tetrahydro-3-methyl-1H,7H-pyrano[4,3-b]benzopyran-1-one monohydrate, CP2 monohydrate
• Fórmula empírica (Notação de Hill): C₂₁H₂₃N₅O₃ · H₂O
• Número CAS: 603113-07-1
• Peso molecular: 411.45
• Número MDL: MFCD11045285
• Código UNSPSC: 12352200
• ID de substância PubChem: 329775077
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: solid
• solubilidade: DMSO: >10 mg/mL
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.C[C@H](Cn1cnc(N)c2ncnc12)[C@H]3CCC4=CC5=C(O[C@H]4C3)C=C(C)OC5=O
• InChI: 1S/C21H23N5O3.H2O/c1-11(8-26-10-25-19(22)18-20(26)24-9-23-18)13-3-4-14-6-15-17(29-16(14)7-13)5-12(2)28-21(15)27;/h5-6,9-11,13,16H,3-4,7-8,22H2,1-2H3;1H2/t11?,13-,16-;/m0./s1
• chave InChI: WIRCSRUVUSUQDQ-HTIJIITDSA-N

Descrição

Ações bioquímicas/fisiológicas

Aminopurinyl pyranobenzopyranone monohydrate is an inhibitor of Aβ oligomer-induced cytotoxicity. It is a new Alzheimer′s research tool and potential therapeutic agent.

Aminopurinyl pyranobenzopyranone monohydrate is an inhibitor of Aβ oligomer-induced cytotoxicity. It is a new Alzheimer′s research tool and potential therapeutic agent. Aminopurinyl pyranobenzopyranone monohydrate acts by inhibiting growth of Aβ oligomers and/or by preventing their toxic conformation or interaction with cellular substrates.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H300
• Declarações de precaução: P264 - P301 + P310
• Classificações de perigo: Acute Tox. 2 Oral
• Código de classe de armazenamento: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges