C2854

Caspase 2 human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution, >1000 units/mg protein

• Sinônimo(s): Ich-1, Nedd2
• Número MDL: MFCD02686998
• Código UNSPSC: 12352200

Propriedades

• recombinante: expressed in E. coli
• Ensaio: ≥95% (SDS-PAGE)
• Formulário: buffered aqueous solution
• atividade específica: >1000 units/mg protein
• peso molecular: inactive proenzyme 56 kDa (active form consists of 17 kDa and 10 kDa subunits); ≥30 kDa
• nº de adesão UniProt: P42575
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... CASP2(835)

Descrição

Ações bioquímicas/fisiológicas

Caspase 2 plays a major role in both positive and negative regulation of programmed cell death. It exists as two spliced variants, Ich-1L (long) and Ich-1S (short). Functionally, the two forms differ in that overexpression of the long form will induce apoptosis, while overexpression of the short form suppresses cell death.

Caspase 2 plays a major role in both positive and negative regulation of programmed cell death; exists as two spliced variants, Ich-1L (long) and Ich-1S (short).

Definição da unidade

One unit will hydrolyze one nmol of N-Acetyl-Val-Asp-Val-Ala-Asp-AFC per min at pH 7.5 at 25 °C.

forma física

Solution in 25 mM HEPES, pH 7.5, 0.15 M NaCl, 5 mM dithiothreitol, 10% sucrose, with 0.5 mg bovine serum albumin

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable