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A5783

Sigma-Aldrich

Albumin, lactosyl bovine

lyophilized powder

Sinônimo(s):

Albumin-N-1-(deoxylactitol)

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About This Item

Número MDL:
Código UNSPSC:
12352202

forma

lyophilized powder

Nível de qualidade

composição

Protein, ~85% biuret

Extensão da rotulagem

10-20 mol disaccharide per mol albumin

solubilidade

H2O: soluble 50 mg/mL

temperatura de armazenamento

−20°C

Descrição geral

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein has an amazing ability to bind to ligands.

Aplicação

Bovine serum albumin (BSA) is extensively used for drug delivery since it is widely available, cheap and easily purified, has ligand-binding properties, and is widely accepted in the pharmaceutical industry.
Albumin was used in a study to test the transfer mechanism of regulated blood-cerebrospinal fluid in immature rats.

Ações bioquímicas/fisiológicas

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.

Embalagem

Package size based on protein content

forma física

Lyophilized powder containing citrate buffer salts

Nota de preparo

Prepared from albumin (A 7638) and α-lactose coupled via reductive amination.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves


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M D Habgood et al.
The Journal of physiology, 456, 181-192 (1992-10-01)
1. The transfer of albumin between the blood and the cerebrospinal fluid (CSF) has been investigated in neonatal (3 days old) and juvenile (20 days old) rats. At both stages of postnatal development, all of the albumin present in the
Yuangang Zu et al.
International journal of nanomedicine, 8, 1207-1222 (2013-04-10)
The livertaxis of glycyrrhizic acid-conjugated bovine serum albumin (GL-BSA) has been reported in the literature. Now, in this paper, we describe a novel type of drug-targeted delivery system containing 10-hydroxycamptothecin (HCPT) with liver tumor targeting. First, GL was coupled to
Proteins containing reductively aminated disaccharides. Synthesis and chemical characterization.
B A Schwartz et al.
Archives of biochemistry and biophysics, 181(2), 542-549 (1977-06-01)
Karolina A Majorek et al.
Molecular immunology, 52(3-4), 174-182 (2012-06-09)
Serum albumin (SA) is the most abundant plasma protein in mammals. SA is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules. Due to

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