A3097

[Pro¹⁸, Asp²¹]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

• Fórmula empírica (Notação de Hill): C₃₃H₄₃N₅O₈
• Número CAS: 182912-74-9
• Peso molecular: 637.72
• Número MDL: MFCD01862668
• Código UNSPSC: 12352200

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: solid
• nº de adesão UniProt: P05067
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O
• Informações sobre genes: human ... APP(351)

Descrição

Amino Acid Sequence

Leu-Pro-Phe-Phe-Asp

Ações bioquímicas/fisiológicas

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.