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Merck
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Documentos

A170

Sigma-Aldrich

Aminorex

solid

Sinônimo(s):

4,5-Dihydro-5-phenyl-2-oxazolamine, Aminoxaphen

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About This Item

Fórmula empírica (Notação de Hill):
C9H10N2O
Número CAS:
2207-50-3
Peso molecular:
162.19
Número MDL:
MFCD00214070
Código UNSPSC:
12352200

forma

solid

controle de medicamentos

USDEA Schedule I; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

cor

white

solubilidade

0.1 M HCl: soluble
H2O: insoluble
ethanol: soluble

cadeia de caracteres SMILES

NC1=NCC(O1)c2ccccc2

InChI

1S/C9H10N2O/c10-9-11-6-8(12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H2,10,11)

chave InChI

SYAKTDIEAPMBAL-UHFFFAOYSA-N

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Substratos

Anorexic; a substrate of the serotonin transporter that also releases serotonin from platelets.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H300 + H310 + H330

Classificações de perigo

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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E K Weir et al.
Circulation, 94(9), 2216-2220 (1996-11-01)
The appetite suppressant aminorex fumarate is thought to have caused an epidemic of pulmonary hypertension in Europe in the 1960s. More recently, pulmonary hypertension has been described in some patients taking other amphetamine-like, anorexic agents: fenfluramine and its d-isomer, dexfenfluramine.
S Friström et al.
Acta pharmacologica et toxicologica, 41(3), 218-224 (1977-09-01)
The effect on 5-hydroxytryptamine release from rabbit platelets to plasma of ten known sympathomimetic or anorectic phenethylamines and eight N- or O-acetyl derivatives of these substances were studied in order to find possible structure-action relationships and a possible correlation to
S M Paul et al.
Science (New York, N.Y.), 218(4571), 487-490 (1982-10-29)
Saturable and stereospecific binding sites for (+)-[3H]amphetamine were demonstrated in membrane preparations from rat brain. The density of these binding sites varies among brain regions and is highest in the hypothalamus and brainstem. Specific (+)-[3H]amphetamine binding in hypothalamus is largely
E N M Ho et al.
Analytica chimica acta, 638(1), 58-68 (2009-03-21)
Administration studies of levamisole in horses were carried out using two different levamisole preparations, namely, levamisole hydrochloride oral bolus and levamisole phosphate injectable solution. These preparations were analysed in detail for the presence of aminorex-like impurities. Both levamisole preparations were
Aminorex to fen/phen: an epidemic foretold.
A P Fishman
Circulation, 99(1), 156-161 (1999-01-13)
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