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352M-9

Napsin A (MRQ-60) Mouse Monoclonal Antibody

Name: Napsin A (MRQ-60) Mouse Monoclonal Antibody
Brand: SIGMA

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About This Item

Código UNSPSC:

12352203

NACRES:

NA.41

Produtos recomendados

Slide 1 of 1

1 of 1

Sigma-Aldrich

SAB5600254

Anti-Napsin-A antibody, Rabbit monoclonal

fonte biológica

mouse

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

MRQ-60, monoclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

forma

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (352M-94)
vial of 0.5 mL concentrate (352M-95)
bottle of 1.0 mL predilute (352M-97)
vial of 1.0 mL concentrate (352M-96)
bottle of 7.0 mL predilute (352M-98)

fabricante/nome comercial

Cell Marque^™

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG1κ

controle

lung adenocarcinoma, renal cell carcinoma

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

cytoplasmic

Informações sobre genes

human ... NAPSA(9476)

Descrição geral

Napsin is a pepsin-like aspartic proteinase in the A1 clan of the AA clade ofproteinases. Napsin A is involved in processing propeptide pulmonary surfactant protein B(proSP-B) in the lung. In normal, benign tissue, Napsin A has expressed in type II pneumocytesof the lung and proximal tubules of the kidney. Napsin A is a useful marker for lungadenocarcinoma.

Qualidade

IVD

RUO

Ligação

Napsin A Positive Control Slides, Product No. 352S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung.

Frank Brasch et al.

The Journal of biological chemistry, 278(49), 49006-49014 (2003-09-18)

Surfactant protein B (SP-B) is a critical component of pulmonary surfactant, and a deficiency of active SP-B results in fatal respiratory failure. SP-B is synthesized by type-II pneumocytes as a 42-kDa propeptide (proSP-B), which is posttranslationally processed to an 8-kDa

Subclassification of non-small cell lung carcinomas lacking morphologic differentiation on biopsy specimens: Utility of an immunohistochemical panel containing TTF-1, napsin A, p63, and CK5/6.

Sanjay Mukhopadhyay et al.

The American journal of surgical pathology, 35(1), 15-25 (2010-12-18)

The availability of targeted therapies has created a need for precise subtyping of non-small cell lung carcinomas (NSCLCs). The aim of this study was to assess the utility of immunohistochemical markers in subtyping poorly differentiated NSCLC and to compare the

Napsin A (TA02) is a useful alternative to thyroid transcription factor-1 (TTF-1) for the identification of pulmonary adenocarcinoma cells in pleural effusions.

Annika Dejmek et al.

Diagnostic cytopathology, 35(8), 493-497 (2007-07-20)

The purpose of this study was to test napsin A as a diagnostic marker of metastatic lung adenocarcinoma in pleural effusions, and to compare its performance with TTF-1. Napsin A and TTF-1 reactivities were determined immunohistochemically on formalin-fixed paraffin embedded

Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma.

Justin A Bishop et al.

Human pathology, 41(1), 20-25 (2009-09-11)

Recent advances in the treatment of pulmonary adenocarcinoma have increased the need for accurate typing of non-small cell carcinomas. Immunohistochemistry for thyroid transcription factor-1 is widely used in the diagnosis of pulmonary adenocarcinomas because it marks approximately 75% of lung

Pulmonary adenocarcinomas with enteric differentiation: histologic and immunohistochemical characteristics compared with metastatic colorectal cancers and usual pulmonary adenocarcinomas.

Kentaro Inamura et al.

The American journal of surgical pathology, 29(5), 660-665 (2005-04-16)

Primary pulmonary adenocarcinomas with enteric differentiation (PAED) are mainly composed of tall-columnar cells that show similarity to intestinal epithelia and colorectal carcinomas. In this study, we analyzed the immunostaining profiles of 7 PAEDs in comparison with 14 metastatic colorectal carcinomas

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