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Y0001576

Oxcarbazepine

Name: Oxcarbazepine
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide, Oxacarbazepine

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About This Item

Fórmula empírica (Notação de Hill):

C₁₅H₁₂N₂O₂

Número CAS:

28721-07-5

Peso molecular:

252.27

Número MDL:

MFCD00865307

Código UNSPSC:

41116107

ID de substância PubChem:

329831491

NACRES:

NA.24

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Supelco

O-039

Oxcarbazepine-¹³C₆ solution

PHL89566

Aristolochic acid II

S859613

2-(ANILINOMETHYL)PHENOL

Y0001014

Amphotericin B for peak identification

Sigma-Aldrich

A5512

Aristolochic acid I

Y0000386

Foeniculin for peak identification

Sigma-Aldrich

5.08508

Zonisamide

Y0001044

Oxymetazoline impurity A

Y0000272

Oxaliplatin impurity B

grau

pharmaceutical primary standard

família API

oxcarbazepine

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O=C1CC2=C(C=CC=C2)N(C(N)=O)C3=CC=CC=C31

InChI

1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)

chave InChI

CTRLABGOLIVAIY-UHFFFAOYSA-N

Informações sobre genes

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Oxcarbazepine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Anticonvulsant, antineuralgic. Inhibits veratrine-induced transmitter release.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

produto relacionado

Nº do produto

Descrição

Preços

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P264 - P270 - P301 + P312 - P501

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Choose from one of the most recent versions:

Certificados de análise (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine.

Gaetano Zaccara et al.

Seizure, 22(7), 528-536 (2013-04-30)

Analysis of overall tolerability and neurological adverse effects (AEs) of eslicarbazepine acetate (ESL), lacosamide (LCM) and oxcarbazepine (OXC) from double-blind, placebo-controlled trials. Indirect comparisons of patients withdrawing because of AEs, and the incidence of some vestibulocerebellar AEs between these three

Oxcarbazepine in the treatment of bipolar disorder: a review.

Wetid Pratoomsri et al.

Canadian journal of psychiatry. Revue canadienne de psychiatrie, 51(8), 540-545 (2006-08-29)

To review the data on the efficacy of oxcarbazepine (OXC) in bipolar disorder (BD) and to provide recommendations for clinicians on the use of this medication in treating BD. Using the terms oxcarbazepine and bipolar disorder, oxcarbazepine and mania, or

Oxcarbazepine in bipolar disorder: a critical review of the literature.

Marianna Mazza et al.

Expert opinion on pharmacotherapy, 8(5), 649-656 (2007-03-23)

Oxcarbazepine (OXC) is a keto-congener of carbamazepine, which has fewer side effects and drug interactions. However, the efficacy of OXC in treating bipolar disorder is not as well established as that of carbamazepine. This article is a systematic literature review

Does oxcarbazepine warrant therapeutic drug monitoring? A critical review.

Penny Bring et al.

Clinical pharmacokinetics, 47(12), 767-778 (2008-11-26)

Oxcarbazepine, the 10-keto analogue of carbamazepine, is approved for the treatment of partial seizures or generalized tonic-clonic seizures. The primary metabolite of oxcarbazepine is monohydroxylated derivative (MHD). This review follows a decision-making algorithm to determine if therapeutic drug monitoring of

Oxcarbazepine in neuropathic pain.

Wassim Nasreddine et al.

Expert opinion on investigational drugs, 16(10), 1615-1625 (2007-10-10)

Neuropathic pain is a frequent condition that can result from a variety of underlying conditions and is frequently chronic and difficult to treat. A number of drugs are used to treat neuropathic pain, including anticonvulsants and antidepressants. Oxcarbazepine, a recently

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