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PHR1031

Supelco

(±)-α-Tocoferol

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

DL-all-rac-α-Tocoferol, Vitamina E

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500 MG
R$ 548,00

R$ 548,00

Previsão de entrega em29 de março de 2025

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500 MG
R$ 548,00

About This Item

Fórmula empírica (Notação de Hill):
C29H50O2
Número CAS:
10191-41-0
Peso molecular:
430.71
Beilstein:
94012
Número CE:
233-466-0
Número MDL:
MFCD00006848
Código UNSPSC:
41116107
eCl@ss:
34058016
ID de substância PubChem:
329823061
NACRES:
NA.24

R$ 548,00

Previsão de entrega em29 de março de 2025

Solicite uma grande encomenda

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

300

Agency

traceable to BP 882
traceable to Ph. Eur. T1550000
traceable to USP 1667600

família API

tocopherol

Certificado de análise (CofA)

current certificate can be downloaded

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

densidade

0.950 g/mL at 20 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

chave InChI

GVJHHUAWPYXKBD-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

α-Tocopherol is a powerful biological antioxidant and the most active form of vitamin E in humans.[1]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

α-Tocopherol may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using flow injection chemiluminescence technique.[1]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB3718 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H317

Classificações de perigo

Skin Sens. 1

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Supelco

47785

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Sigma-Aldrich

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Supelco

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PHR1237

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Flow-injection determination of retinol and tocopherol in pharmaceuticals with acidic potassium permanganate chemiluminescence
Waseem A, et al.
Analytical Sciences, 25(3), 407-412 (2009)
Simultaneous determination of retinol and alpha-tocopherol in serum or plasma by liquid chromatography
Catignani LG and Bieri GJ
Clinical Chemistry, 29, 708-712 (1983)
Sam B Weber et al.
Proceedings. Biological sciences, 279(1731), 1077-1084 (2011-09-23)
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Protocolos

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® S

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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