936693

tBuXPhos ChemBeads

• Sinônimo(s): 2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl ChemBeads, tert-Butyl Xphos ChemBeads, t-Bu Xphos ChemBeads, tBuXPhos
• Fórmula empírica (Notação de Hill): C₂₉H₄₅P
• Número CAS: 564483-19-8
• Peso molecular: 424.64
• Número MDL: MFCD06411306
• Código UNSPSC: 12352100

Propriedades

• Nível de qualidade: 100
• Formulário: solid
• composição: , 4-6 wt. % (loading)
• adequação da reação: reagent type: ligand
• cadeia de caracteres SMILES: CC(C)(C)P(C(C)(C)C)C1=C(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)C=CC=C1
• InChI: InChI=1S/C29H45P/c1-19(2)22-17-24(20(3)4)27(25(18-22)21(5)6)23-15-13-14-16-26(23)30(28(7,8)9)29(10,11)12/h13-21H,1-12H3
• chave InChI: SACNIGZYDTUHKB-UHFFFAOYSA-N

Descrição

Descrição geral

The ChemBeads product of tBuXPhos [2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions. Loaded on glass beads for use in high-throughput expermentation (HTE).

Aplicação

tBuXPhos has been used as a ligand in many C-N and C-O bond forming reactions, as well many others including:
- The palladium-catalyzed Tsuji-Trost substitution and cross-coupling of benzylic fluorides.[1]
- The palladium-catalyzed C-N cross-coupling of sulfinamides and aryl halides.[2]
- The protoboration of alkynes.[3]
- ArF-alkynyl coupling with fluorinated aryls.[4]
- The Ni & Ni/Pd reductive coupling of lignan-derived aromatics to biobased platicizers.[5]
- The palladium-catalyzed fluorination of cyclic vinyl triflates.[6]
ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.
For general uses, product is also available in powdered form (638080)

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable