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Merck
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72858

Supelco

2-(2-Methyl-5-nitro-1H-imidazol-1-yl)acetic acid

analytical standard

Sinônimo(s):

1-Carboxymethylmetronidazole, 2-Methyl-5-nitroimidazole-1-acetic acid, Metronidazole-1-acetic acid

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About This Item

Fórmula empírica (Notação de Hill):
C6H7N3O4
Número CAS:
1010-93-1
Peso molecular:
185.14
Beilstein:
613770
Número MDL:
MFCD01721819
Código UNSPSC:
41116107
ID de substância PubChem:
329764410
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

Ensaio

≥97.5% (GC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

Impurezas

≤0.5% water

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

O=C(O)CN1C(C)=NC=C1[N+]([O-])=O

InChI

1S/C6H7N3O4/c1-4-7-2-5(9(12)13)8(4)3-6(10)11/h2H,3H2,1H3,(H,10,11)

chave InChI

RVEGZXNRNWUYKI-UHFFFAOYSA-N

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Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H319

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCG1281
BCCF1730
BCBX5230
BCBQ9694V
BCBL3638V

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Visite a Biblioteca de Documentos

B Fredricsson et al.
Gynecologic and obstetric investigation, 24(3), 200-207 (1987-01-01)
Metronidazole kinetics was studied in 5 healthy women after a single dose given intravenously, orally or vaginally, 500, 400 and 500 mg, respectively. Serum levels of the drug and of its hydroxy and acid metabolites were assessed. The results after
R A Gibson et al.
Clinical chemistry, 30(5), 784-787 (1984-05-01)
Metronidazole and its known metabolites in plasma can be rapidly separated by a "high-pressure" liquid-chromatographic method that can also be adapted for rapid determination of tinidazole. Samples deproteinized with trichloroacetic acid (50 g/L final concentration) undergo isocratic separation on a
B Salvesen et al.
Scandinavian journal of gastroenterology. Supplement, 91, 31-43 (1984-01-01)
A high-performance liquid chromatography (HPLC) method for the assay of metronidazole and its 2-hydroxymethyl metabolite in sera was compared with a microbiological method, an agar well diffusion technique with Clostridium perfringens as indicator strain. The HPLC technique involves separation of
O Eradiri et al.
Biopharmaceutics & drug disposition, 8(3), 249-259 (1987-05-01)
The pharmacokinetics of metronidazole (MTZ) were studied in six Crohn's disease patients after multiple oral daily doses of 250, 500, 750, and 1000 mg day-1. Pharmacokinetic indices were found to be independent of the dose administered. The half-life, volume of
D R Guay et al.
Antimicrobial agents and chemotherapy, 25(3), 306-310 (1984-03-01)
The pharmacokinetics of metronidazole, its biologically active alcohol metabolite, and its inactive acid metabolite were studied in five noninfected patients undergoing continuous ambulatory peritoneal dialysis and five patients undergoing hemodialysis. The latter were studied on off-dialysis days as a control
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